Alcohol and opioids The concomitant utilization of alcohol and opioids raises the chance of sedation, respiratory melancholy, coma and death as a consequence of additive CNS depressant effect. Concomitant use with alcohol is not recommended (see area 4.four).
The leaflet will state during the “pregnancy and breast-feeding” subsection in the portion two “Prior to getting your drugs”: Co-codamol is contraindicated in breast-feeding
Taking heroin Whilst you're on prescribed co-codamol is especially harmful. You're much more prone to get every one of the Unintended effects on the codeine in co-codamol, including addiction.
You are getting drugs to take care of despair referred to as MAOIs (monoamine oxidase inhibitors) or have taken them in the last two weeks. MAOIs are medicines such as moclobemide, phenelzine or tranylcypromine.
It's best to halt drinking alcohol in the course of the very first couple days of therapy till you see how co-codamol influences you.
Caution needs to be taken when paracetamol is utilised concomitantly with flucloxacillin as concurrent consumption has long been connected with large anion gap metabolic acidosis as a result of pyroglutamic acidosis, specifically in individuals with pitfalls components (see portion four.4)
If you want to journey overseas with any opioid medication, which includes co-codamol, constantly Verify the constraints of the region you are travelling to. Failure to comply with the right processes may end up in significant fines and imprisonment.
Your prescriber will discuss with you how to progressively minimize your dose ahead of stopping the medicine. It is vital that you do not halt getting the medication abruptly as you can be far more prone to expertise withdrawal signs.
If opioid use is necessary for a protracted period of time in the pregnant lady, advise the patient of the risk of neonatal opioid withdrawal syndrome and be certain that appropriate treatment might be available.
Additional aid and checking could be required when prescribing for people at risk of opioid misuse.
Don't instantly prevent getting this medication. If you wish to stop getting this drugs, examine this with your prescriber very first. They'll show you how To do that, usually by lessening the dose slowly in order that any unpleasant withdrawal consequences are stored to the bare minimum.
If you will get any Unintended effects check with your doctor or pharmacist. This consists of any feasible Unwanted side effects not outlined in this leaflet. See part 4.
Co-codamol really should not be employed for pain relief in small children and adolescents soon after removal in their tonsils or adenoids as a result of Obstructive Sleep Apnoea Syndrome.
• You happen to be allergic to your Lively substances or any of one other components with your medication (shown in Part six). Signs of here an allergic reaction contain a rash and respiration difficulties. There can be swelling on the legs, arms, experience, throat or tongue.